PI: Sean Collins, MD

Sponsor: PCORI 

Get with the Guidelines in Emergency Department Patients with Heart Failure (GUIDED HF) is a multicenter, randomized, 1:1 trial comparing 1) standardized emergency department (ED) discharge vs. 2) a tailored discharge plan implementing get with the guidelines heart failure (GWTG:HF) recommendations via a transition nurse coordinator (TNC) led study team in patients with AHF discharged from the ED. 


The trial will enroll 700 patients discharged from the ED with AHF, as diagnosed by the treating physician. Entry criteria will permit enrollment of ED patients: 1) in whom AHF is diagnosed, 2) for whom ED physicians intend to discharge from the ED or after a period of observation of less than 24 hours, 3) who are low-risk and will not have difficulties complying with the protocol due to psychiatric disease, dementia, or proximity to the enrolling institution, making the TNC home visit problematic. The primary outcome is time to 90-day ED revisit, hospital admission or CV death, and secondary outcomes include HF quality of life, HF knowledge and patient satisfaction.


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